Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 CausalMutation group CLINVAR
Entrez Id: 4214
Gene Symbol: MAP3K1
MAP3K1 		0.530 CausalMutation group CGI
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.500 CausalMutation group CLINVAR Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. 11504908 2001
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.500 CausalMutation group CLINVAR Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. 18571837 2008
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.500 CausalMutation group CLINVAR Activating ESR1 mutations in hormone-resistant metastatic breast cancer. 24185510 2013
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.500 CausalMutation group CLINVAR
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.500 CausalMutation group CLINVAR Germline CHEK2 mutations in Jewish Ashkenazi women at high risk for breast cancer. 18085035 2007
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 CausalMutation group CLINVAR [Simple and rapid technic of grouping of streptococci]. 824983 1976
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.500 CausalMutation group CLINVAR Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline CHEK2:c.1100delC mutation and a concomitant diagnosis of metastatic invasive ductal breast carcinoma. 28514723 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.500 CausalMutation group CLINVAR Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. 16551709 2006
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.500 CausalMutation group CLINVAR The selective class I PI3K inhibitor CH5132799 targets human cancers harboring oncogenic PIK3CA mutations. 21558396 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.500 CausalMutation group CLINVAR Nonsense-mediated mRNA decay: terminating erroneous gene expression. 15145354 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.500 CausalMutation group CLINVAR Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas. 16397024 2006
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.500 CausalMutation group CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370 2005
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 CausalMutation group CLINVAR Purification and characterization of a new sodium-transport decarboxylase. Methylmalonyl-CoA decarboxylase from Veillonella alcalescens. 6852015 1983
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 CausalMutation group CLINVAR Nonsense-mediated mRNA decay: terminating erroneous gene expression. 15145354 2004
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 CausalMutation group CLINVAR Chromosome damage in G0 X-irradiated lymphocytes from patients with hereditary retinoblastoma. 6455195 1981
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 CausalMutation group CLINVAR Characteristics and spectrum of BRCA1 and BRCA2 mutations in 3,922 Korean patients with breast and ovarian cancer. 22798144 2012
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.500 CausalMutation group CLINVAR Breast tumors which arise in carriers of CHEK2 mutations seem to be similar to those of breast cancers in the population at large. 16914568 2006
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 CausalMutation group CLINVAR BRCT repeats as phosphopeptide-binding modules involved in protein targeting. 14576432 2003
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.500 CausalMutation group CLINVAR Nonsense-mediated mRNA decay: terminating erroneous gene expression. 15145354 2004
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.500 CausalMutation group CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058 2010
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.500 CausalMutation group CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589 2012
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 CausalMutation group CLINVAR [The measuring for depth of papillary excavation by microcomputer (author's transl)]. 7257965 1980
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.500 CausalMutation group CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016